Pharmacokinetic and Bioavailability Studies of Embelin after Intravenous and Oral Administration to Rats

Embelin exhibits the broad bioactivities such as antitumor, antifertility, antidiabetic, anti-inflammatory, antioxidant, anticonvulsant, anxiolytic, antimicrobial, and hepatoprotective activity. In order to further understand the pharmacokinetic characteristics and oral bioavailability of embelin in vivo , the concentration of embelin in rat plasma was determined by a sensitive high-performance liquid chromatography with diode array detector...