Regulation of transposable elements by DNA modifications

Volume: 20, Issue: 7, Pages: 417 - 431
Published: Jul 1, 2019
Abstract
Maintenance of genome stability requires control over the expression of transposable elements (TEs), whose activity can have substantial deleterious effects on the host. Chemical modification of DNA is a commonly used strategy to achieve this, and it has long been argued that the emergence of 5-methylcytosine (5mC) in many species was driven by the requirement to silence TEs. Potential roles in TE regulation have also been suggested for other...
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Paper Details
Title
Regulation of transposable elements by DNA modifications
Published Date
Jul 1, 2019
Volume
20
Issue
7
Pages
417 - 431
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