Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex

Nature64.80
Volume: 568, Issue: 7750, Pages: 127 - 130
Published: Mar 13, 2019
Abstract
The L-type amino acid transporter 1 (LAT1; also known as SLC7A5) catalyses the cross-membrane flux of large neutral amino acids in a sodium- and pH-independent manner1-3. LAT1, an antiporter of the amino acid-polyamine-organocation superfamily, also catalyses the permeation of thyroid hormones, pharmaceutical drugs, and hormone precursors such as L-3,4-dihydroxyphenylalanine across membranes2-6. Overexpression of LAT1 has been observed in a wide...
Paper Details
Title
Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
Published Date
Mar 13, 2019
Journal
Volume
568
Issue
7750
Pages
127 - 130
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.