Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes

Recent articles have highlighted the lack of reproducibility of data from scientific publications. Here we would argue that a better way to describe and also tackle this matter is to use the term “lack of robustness,” since it points toward potential solutions. Presenting several case reports, we highlight examples with common underlying issues from Novo Nordisk’s experience: animal model variability, reagent quality, and inter-lab variability....