Leptin-induced signaling pathways in cancer cell migration and invasion.
Abstract
Increasing evidence indicates that obesity is associated with tumor development and progression. Leptin is an adipocyte-related hormone with a key role in energy metabolism and whose circulating levels are elevated in obesity. The effect of leptin on cancer progression and metastasis and its underlying mechanisms are still unclear. Leptin can impact various steps in tumor metastasis, including epithelial-mesenchymal transition, cell adhesion to...
Paper Details
Title
Leptin-induced signaling pathways in cancer cell migration and invasion.
Published Date
Mar 15, 2019
Journal
Volume
42
Issue
3
Pages
243 - 260
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Notes
History