Original paper

Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study

Volume: 176, Issue: 6, Pages: 439 - 448
Published: Jun 1, 2019
Abstract
Objective: Cariprazine, a dopamine D3/D2 and 5-HT1A receptor partial agonist, was found to be effective in treating bipolar I depression in a previous phase 2 study. This phase 3 study further assessed the efficacy, safety, and tolerability of cariprazine in bipolar I depression. Methods: In a double-blind placebo-controlled study, adult participants (18–65 years old) who met DSM-5 criteria for bipolar I disorder and a current depressive episode...
Paper Details
Title
Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study
Published Date
Jun 1, 2019
Volume
176
Issue
6
Pages
439 - 448
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