Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease
Abstract
To evaluate DNA methylation sites and gene expression associated with coronary artery disease (CAD) and the possible pathological mechanism involved, we performed (1) genome-wide DNA methylation and mRNA expression profiling in peripheral blood datasets from the Gene Expression Omnibus repository of CAD samples and controls; (2) functional enrichment analysis and differential methylation gene regulatory network construction; (3) validation tests...
Paper Details
Title
Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease
Published Date
Mar 7, 2019
Journal
Volume
11
Issue
5
Pages
1486 - 1500
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