Gamma Knife Radiosurgery for the Management of More Than 15 Cerebral Metastases

The number of metastases that can be treated safely and effectively with Gamma Knife stereotactic radiosurgery (SRS) remains controversial despite continuing evidence to support its expanded utilization. We endeavored to elucidate the survival outcomes for patients who presented with ≥15 brain metastases at the time of initial SRS. This retrospective analysis reviewed patients treated for ≥15 brain metastases originating from breast cancer, lung...