Affinity-Based Functionalization of Biomedically Utilized Micelles Composed of Triblock Copolymers through Polymer-Binding Peptides

Polymeric micelles and vesicles that are self-assembled from amphiphilic block copolymers are frequently used in biomedical applications. Poly(ethylene oxide) (PEO)–poly(propylene oxide) (PPO)–PEO, so-called Pluronic, is a Food and Drug Administration approved triblock copolymer utilized in biomedical applications. However, the control of drug loading and surface functionalization of micelles remain challenging due to structural limitations. In...