Clinical determinants for successful circulating tumor DNA analysis in prostate cancer
Abstract
Plasma-based cell-free DNA is an attractive biospecimen for assessing somatic mutations due to minimally-invasive real-time sampling. However, next generation sequencing (NGS) of cell-free DNA (cfDNA) may not be appropriate for all patients with advanced prostate cancer (PC).Blood was obtained from advanced PC patients for plasma-based sequencing. UW-OncoPlex, a ∼2 Mb multi-gene NGS panel performed in the CLIA/CAP environment, was optimized for...
Paper Details
Title
Clinical determinants for successful circulating tumor DNA analysis in prostate cancer
Published Date
Mar 13, 2019
Journal
Volume
79
Issue
7
Pages
701 - 708
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