Dietary fatty acids fine-tune Piezo1 mechanical response
Abstract
Mechanosensitive ion channels rely on membrane composition to transduce physical stimuli into electrical signals. The Piezo1 channel mediates mechanoelectrical transduction and regulates crucial physiological processes, including vascular architecture and remodeling, cell migration, and erythrocyte volume. The identity of the membrane components that modulate Piezo1 function remain largely unknown. Using lipid profiling analyses, we here...
Paper Details
Title
Dietary fatty acids fine-tune Piezo1 mechanical response
Published Date
Mar 13, 2019
Journal
Volume
10
Issue
1
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