Deregulated GATA6 modulates stem cell‐like properties and metabolic phenotype in hepatocellular carcinoma
Abstract
Accumulating evidence illustrates the significance of cell plasticity in the molecular biology of liver cancer. Reprogramming of mature parenchymal cells to a less differentiated state by key molecular targets contributes to the pathogenesis of hepatocellular carcinoma (HCC). Hereby, we investigated the role of GATA6, a transcription factor implicated in hepatocyte lineage specification, in HCC. Our results demonstrated a lower expression of...
Paper Details
Title
Deregulated GATA6 modulates stem cell‐like properties and metabolic phenotype in hepatocellular carcinoma
Published Date
Mar 28, 2019
Volume
145
Issue
7
Pages
1860 - 1873
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