Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes

Volume: 35, Issue: 6, Pages: 541 - 564
Published: Feb 25, 2019
Abstract
2-Chloroethyl ethyl sulfide (CEES) is a well-known chemical warfare agent that induces cellular stress in exposed individuals. However, molecular mechanisms of CEES-induced oxidative stress–mediated metabolic deregulation are not clearly elucidated. Here we investigated CEES-induced free radical production act as key functional mediators of metabolic stress via Erk1/2 mitogen–activated protein kinases (MAPKs) and phosphatidylinositol-3-kinase...
Paper Details
Title
Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes
Published Date
Feb 25, 2019
Volume
35
Issue
6
Pages
541 - 564
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