Fatal dysfunction and disintegration of thrombin-stimulated platelets
Abstract
Platelets play a key role in the formation of hemostatic clots and obstructive thrombi as well as in other biological processes. In response to physiological stimulants, including thrombin, platelets change shape, express adhesive molecules, aggregate, and secrete bioactive substances, but their subsequent fate is largely unknown. Here we examined late-stage structural, metabolic, and functional consequences of thrombin-induced platelet...
Paper Details
Title
Fatal dysfunction and disintegration of thrombin-stimulated platelets
Published Date
Feb 21, 2019
Journal
Volume
104
Issue
9
Pages
1866 - 1878
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Notes
History