Loss of HER2 after HER2-targeted treatment

Volume: 175, Issue: 2, Pages: 401 - 408
Published: Feb 26, 2019
Abstract
HER2 expression has been reported to be discordant between primary tumor and metastatic tissue. HER2 discordance and relation to HER2-targeted treatment was investigated in 227 patients with primary breast cancer. HER2 discordance between primary biopsy and second biopsy after neoadjuvant or adjuvant treatment was observed in 20.7%. This discordance was related only to the use of HER2-targeted treatment: 30 of 33 (90.9%) women with downgraded...
Paper Details
Title
Loss of HER2 after HER2-targeted treatment
Published Date
Feb 26, 2019
Volume
175
Issue
2
Pages
401 - 408
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