Nitro-fatty acids protect against steatosis and fibrosis during development of nonalcoholic fatty liver disease in mice
Abstract
BackgroundNonalcoholic fatty liver disease (NAFLD) and resulting nonalcoholic steatohepatitis (NASH) are reaching global epidemic proportions. Lack of non-invasive diagnostic tools and effective therapies constitute two of the major hurdles for a bona fide treatment and a reversal of NASH progression and/or regression of the disease. Nitro-oleic acid (OA-NO2) has been proven effective in multiple experimental models of inflammation and fibrosis....
Paper Details
Title
Nitro-fatty acids protect against steatosis and fibrosis during development of nonalcoholic fatty liver disease in mice
Published Date
Mar 1, 2019
Journal
Volume
41
Pages
62 - 72
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Notes
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