Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment
Abstract
Lauroyl-gemcitabine lipid nanocapsules (GemC12-LNC) hydrogel, administered intratumorally or perisurgically in the tumor resection cavity, increases animal survival in several orthotopic GBM models. We hypothesized that GemC12-LNC can be used as nanodelivery platform for other drugs, to obtain a combined local therapeutic approach for GBM. Paclitaxel (PTX) was selected as a model molecule and PTX-GemC12-LNC formulation was evaluated in terms of...
Paper Details
Title
Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment
Published Date
Mar 1, 2019
Volume
559
Pages
220 - 227
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