TNF induces production of type 2 cytokines in human group 2 innate lymphoid cells

It is well recognized that group 2 innate lymphoid cells (ILC2s) play a key role in both innate immunity to protect against parasitic pathogens and pathologic processes for many type 2 inflammatory diseases, including asthma and chronic rhinosinusitis with nasal polyps (CRSwNP).1Kabata H. Moro K. Koyasu S. The group 2 innate lymphoid cell (ILC2) regulatory network and its underlying mechanisms.Immunol Rev. 2018; 286: 37-52Crossref PubMed Scopus...