Polo‑like kinase�4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma

Published: Feb 14, 2019
Abstract
Glioblastoma (GBM) is one of the most malignant tumors in adults, associated with severe outcomes (median survival, <2 years). Multiple mechanisms are known to be involved in tumor recurrence and treatment resistance in GBM, however, the key regulator for GBM tumorigenesis and therapy resistance remains unclear. To clarify a novel potential functional mechanism of GBM recurrence, a wide range of experiments including in vitro molecular...
Paper Details
Title
Polo‑like kinase�4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma
Published Date
Feb 14, 2019
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