EpiMethEx: a tool for large-scale integrated analysis in methylation hotspots linked to genetic regulation
Abstract
DNA methylation is an epigenetic mechanism of genomic regulation involved in the maintenance of homeostatic balance. Dysregulation of DNA methylation status is one of the driver alterations occurring in neoplastic transformation and cancer progression. The identification of methylation hotspots associated to gene dysregulation may contribute to discover new prognostic and diagnostic biomarkers, as well as, new therapeutic targets.We present...
Paper Details
Title
EpiMethEx: a tool for large-scale integrated analysis in methylation hotspots linked to genetic regulation
Published Date
Feb 1, 2019
Journal
Volume
19
Issue
S13
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Notes
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