doi.org/10.1053/j.gastro.2019.02.003
Original paper

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level

..., Christoph Neumann-Haefelin
36
Gastroenterology25.70
Volume: 156, Issue: 6, Pages: 1820 - 1833
Published: May 1, 2019
Abstract
Background & AimsHepatitis D virus (HDV) superinfection in patients with hepatitis B virus (HBV) is associated with rapid progression to liver cirrhosis and hepatocellular carcinoma. Treatment options are limited, and no vaccine is available. Although HDV-specific CD8+ T cells are thought to control the virus, little is known about which HDV epitopes are targeted by virus-specific CD8+ T cells or why these cells ultimately fail to control the...
Paper Fields
Paper Details
Title
Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level
DOI
doi.org/10.1053/j.gastro.2019.02.003
Published Date
May 1, 2019
Journal
Gastroenterology
Volume
156
Issue
6
Pages
1820 - 1833
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