Design of novel organic–inorganic composite bone cements with high compressive strength, in vitro bioactivity and cytocompatibility

In this work, novel bioactive organic–inorganic composite bone cements consisting of tricalcium silicate (C 3 S), sodium alginate (SA), and calcium sulfate hemihydrate (CS) were successfully fabricated for the first time via a special method designing material composition and internal structure simultaneously, which was intended to enhance mechanical performance by combining progressive hydration process of C 3 S with distinctive gelation...