Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent
Abstract
Breast cancer is the most diagnosed type of cancer among women for which an exhaustive cure has not been discovered yet. Nowadays, tamoxifen still represents the gold standard for breast cancer therapy; it acts on both estrogen receptor-positive and estrogen receptor-negative breast cancers. Unfortunately, its toxicity and the related chemoresistance undermine its antitumor potential. In this paper, new tamoxifen-based derivatives with a rigid...
Paper Details
Title
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent
Published Date
May 1, 2019
Journal
Volume
86
Pages
538 - 549
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Notes
History