Rho Flares Repair Local Tight Junction Leaks
Abstract
Tight junctions contribute to epithelial barrier function by selectively regulating the quantity and type of molecules that cross the paracellular barrier. Experimental approaches to evaluate the effectiveness of tight junctions are typically global, tissue-scale measures. Here, we introduce Zinc-based Ultrasensitive Microscopic Barrier Assay (ZnUMBA), which we used in Xenopus laevis embryos to visualize short-lived, local breaches in epithelial...
Paper Details
Title
Rho Flares Repair Local Tight Junction Leaks
Published Date
Feb 1, 2019
Journal
Volume
48
Issue
4
Pages
445 - 459.e5
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Notes
History