Severe Necrotic Reaction to 23-Valent Polysaccharide Pneumococcal Vaccine in a Patient with STAT3 Deficiency

Volume: 7, Issue: 5, Pages: 1631 - 1632
Published: May 1, 2019
Abstract
Autosomal-dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency caused by loss-of-function mutations in signal transducer and activator of transcription 3 (STAT3) leading to defective TH17 immunity and abnormal B-cell function. Although immunoglobulin levels are generally normal in AD-HIES, patients are variably affected by specific antibody deficiency. Thus, boosting their antipneumococcal immunity is important to prevent...
Paper Details
Title
Severe Necrotic Reaction to 23-Valent Polysaccharide Pneumococcal Vaccine in a Patient with STAT3 Deficiency
Published Date
May 1, 2019
Volume
7
Issue
5
Pages
1631 - 1632
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