Immune aging in diabetes and its implications in wound healing
Abstract
Immune systems have evolved to recognize and eliminate pathogens and damaged cells. In humans, it is estimated to recognize 109 epitopes and natural selection ensures that clonally expanded cells replace unstimulated cells and overall immune cell numbers remain stationary. But, with age, it faces continuous repertoire restriction and concomitant accumulation of primed cells. Changes shaping the aging immune system have bitter consequences...
Paper Details
Title
Immune aging in diabetes and its implications in wound healing
Published Date
Mar 1, 2019
Journal
Volume
200
Pages
43 - 54
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Notes
History