Evidence of early microstructural white matter abnormalities in multiple sclerosis from multi-shell diffusion MRI
Abstract
Irreversible white matter (WM) damage, including severe demyelination and axonal loss, is a main determinant of long-term disability in multiple sclerosis (MS). Non-invasive detection of changes in microstructural WM integrity in the disease is challenging since commonly used imaging metrics lack the necessary sensitivity, especially in the early phase of the disease. This study aims at assessing microstructural WM abnormalities in early-stage...
Paper Details
Title
Evidence of early microstructural white matter abnormalities in multiple sclerosis from multi-shell diffusion MRI
Published Date
Jan 1, 2019
Journal
Volume
22
Pages
101699 - 101699
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