Effects of APOE on cognitive aging in community-dwelling older adults.
Abstract
The apolipoprotein E (APOE) gene is an established risk factor for sporadic Alzheimer's disease, with elevated risk for ε4-carriers and reduced risk for ε2-carriers. However, it is unclear whether APOE modifies risk for cognitive decline in normal aging. The objective of this study was to determine whether ε2 and ε4 are associated with rates of normal cognitive aging, and whether associations of ε4 with cognitive decline are modified by sex,...
Paper Details
Title
Effects of APOE on cognitive aging in community-dwelling older adults.
Published Date
Mar 1, 2019
Journal
Volume
33
Issue
3
Pages
406 - 416
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