Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer
Abstract
Approximately 70% of patients with advanced breast cancer develop bone metastases, accompanied by complications, such as bone pain, fracture, and hypercalcemia. However, our understanding of the molecular mechanisms that govern this process remains fragmentary. Osterix (Osx) is a zinc finger-containing transcription factor essential for osteoblast differentiation and bone formation. Here, we identified the functional roles of Osx in facilitating...
Paper Details
Title
Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer
Published Date
Jan 10, 2019
Journal
Volume
10
Issue
1
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