Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma
Abstract
Hepatocellular carcinoma (HCC) is generally accompanied by high mortality and low cure rate. CCAAT enhancer-binding proteins (CEBPs) are transcriptional regulators that play a key role in maintaining liver function. Altered expression of C/EBPα and C/EBPβ occurs in many tumours including HCC. saRNAs are small double-stranded RNAs that enhance target gene expression at the transcriptional level. In this report, we activate CEPBA with saRNAs and...
Paper Details
Title
Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma
Published Date
Jan 14, 2019
Journal
Volume
38
Issue
18
Pages
3446 - 3457
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