Substance P-mediated cardiac mast cell activation: An in vitro study
Abstract
The neuropeptide substance P can induce degranulation of cardiac mast cells at high concentrations. Herein, we seek to further understand substance P activation of cardiac mast cells in the context of other neuropeptides as well as modulation by non-neuropeptides. This is important given the increasingly recognized role of both cardiac mast cells and substance P in adverse cardiac remodeling. To address this, we isolated cardiac mast cells and...
Paper Details
Title
Substance P-mediated cardiac mast cell activation: An in vitro study
Published Date
Apr 1, 2019
Journal
Volume
74
Pages
52 - 59
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