OP0202 Gene expression profiles in primary sjÖgren’s syndrome with and without systemic manifestations

Background

Different phenotypes characterise the clinical spectrum of primary Sjögren’s syndrome (SjS). Patients with a clinical expression limited to glandular features (GFs) are classically distinguished from patients with extra-glandular manifestations (EGMs). The former patients often complain higher level of fatigue and widespread pain (WP). (Segal et al. 2013) This suggests that gene expression pattern may be different in the two...