Imprinted MicroRNA Gene Clusters in the Evolution, Development, and Functions of Mammalian Placenta.
Abstract
In mammals, the expression of a subset of microRNA (miRNA) genes is governed by genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a parent-of-origin manner. Three evolutionarily distinct genomic intervals contain the vast majority of imprinted miRNA genes: the rodent-specific, paternally expressed C2MC located in intron 10 of the Sfmbt2 gene, the primate-specific, paternally expressed C19MC positioned at human...
Paper Details
Title
Imprinted MicroRNA Gene Clusters in the Evolution, Development, and Functions of Mammalian Placenta.
Published Date
Jan 18, 2019
Journal
Volume
9
Pages
706 - 706
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History