Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients

Volume: 40, Issue: 4, Pages: 544 - 550
Published: Jan 9, 2019
Abstract
Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis, caused by various factors, such as the aggressiveness of the disease, the limited therapeutic options and the lack of early detection and risk markers. The ATP binding cassette subfamily C member 2 (ABCC2) protein plays a critical role in response to various drugs and is differentially expressed in gemcitabine sensitive and resistant cells. Moreover, single nucleotide...
Paper Details
Title
Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients
Published Date
Jan 9, 2019
Volume
40
Issue
4
Pages
544 - 550
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