Th17 cell frequency is associated with low bone mass in primary sclerosing cholangitis

Volume: 70, Issue: 5, Pages: 941 - 953
Published: May 1, 2019
Abstract
•Decreased bone mass in patients with PSC is associated with increased bone resorption. •Th17 cell frequency correlates with bone resorption indices in patients with PSC. •Increased osteoclastogenesis is corrected by IL-17 inactivation in Abcb4−/− mice. Background & Aims Osteoporotic fractures are a major cause of morbidity and reduced quality of life in patients with primary sclerosing cholangitis (PSC), a progressive bile duct disease of...
Paper Details
Title
Th17 cell frequency is associated with low bone mass in primary sclerosing cholangitis
Published Date
May 1, 2019
Volume
70
Issue
5
Pages
941 - 953
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