Phosphodiesterase type 5 inhibitor attenuates chronic ischemia‐induced prostatic hyperplasia in a rat model

Volume: 79, Issue: 5, Pages: 536 - 543
Published: Dec 28, 2018
Abstract
Many elderly men suffer from benign prostatic hyperplasia (BPH). Recently, chronic ischemia in the prostate has been suggested to be related to BPH. Thus, the impact of chronic ischemia on the development of prostatic hyperplasia and the efficacy of phosphodiesterase type 5 (PDE5) inhibitor for hyperplasia were evaluated in a rat model with chronic ischemia induced by local atherosclerosis.Eighteen male Sprague-Dawley rats were divided into...
Paper Details
Title
Phosphodiesterase type 5 inhibitor attenuates chronic ischemia‐induced prostatic hyperplasia in a rat model
Published Date
Dec 28, 2018
Volume
79
Issue
5
Pages
536 - 543
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