Clinical association between the metabolite of healthy gut microbiota, 3-indolepropionic acid and chronic kidney disease

Emerging evidence indicates that gut microbiota serves an important role in the development and progression of chronic kidney disease (CKD). Changes to the gut microbial flora can cause the generation of uremic toxins, which contribute to chronic kidney injury. The aim of the current study was to explore the clinical association between metabolites and CKD.Between August 2013 and January 2015, a two-phase case-control study was conducted to...