Proteomics and multivariate modelling reveal sex-specific alterations in distinct regions of human carotid atheroma
Abstract
Atherosclerotic lesions are comprised of distinct regions with different proteomic profiles. Men and women develop differences in lesion phenotype, with lesions from women generally being more stable and less prone to rupture. We aimed to investigate the differences in proteomic profiles between sexes, including distinct lesion regions, to identify altered proteins that contribute to these differences observed clinically. Carotid endarterectomy...
Paper Details
Title
Proteomics and multivariate modelling reveal sex-specific alterations in distinct regions of human carotid atheroma
Published Date
Dec 1, 2018
Journal
Volume
9
Issue
1
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