Robust estimation of hemo-dynamic parameters in traditional DCE-MRI models

In dynamic contrast enhanced (DCE) MRI, separation of signal contributions from perfusion and leakage requires robust estimation of parameters in a pharmacokinetic model. We present and quantify the performance of a method to compute tissue hemodynamic parameters from DCE data using established pharmacokinetic models.We propose a Bayesian scheme to obtain perfusion metrics from DCE MRI data. Initial performance is assessed through digital...