Targeting Cancer Stemness in the Clinic: From Hype to Hope

Volume: 24, Issue: 1, Pages: 25 - 40
Published: Jan 3, 2019
Abstract
Tumors are composed of non-homogeneous cell populations exhibiting varying degrees of genetic and functional heterogeneity. Cancer stem cells (CSCs) are capable of sustaining tumors by manipulating genetic and non-genetic factors to metastasize, resist treatment, and maintain the tumor microenvironment. Understanding the key traits and mechanisms of CSC survival provides opportunities to improve patient outcomes via improved prognostic models...
Paper Details
Title
Targeting Cancer Stemness in the Clinic: From Hype to Hope
Published Date
Jan 3, 2019
Volume
24
Issue
1
Pages
25 - 40
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