A micro RNA cluster in the Fragile‐X region expressed during spermatogenesis targets FMR 1

Volume: 20, Issue: 2
Published: Dec 20, 2018
Abstract
Testis-expressed X-linked genes typically evolve rapidly. Here, we report on a testis-expressed X-linked microRNA (miRNA) cluster that despite rapid alterations in sequence has retained its position in the Fragile-X region of the X chromosome in placental mammals. Surprisingly, the miRNAs encoded by this cluster (Fx-mir) have a predilection for targeting the immediately adjacent gene, Fmr1, an unexpected finding given that miRNAs usually act in...
Paper Details
Title
A micro RNA cluster in the Fragile‐X region expressed during spermatogenesis targets FMR 1
Published Date
Dec 20, 2018
Volume
20
Issue
2
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