Effect of liraglutide on the Janus kinase/signal transducer and transcription activator (JAK/STAT) pathway in diabetic kidney disease in db/db mice and in cultured endothelial cells
Abstract
Background Emerging evidence demonstrates the involvement of Janus tyrosine kinase/signal transducer and transcription activator (JAK/STAT) proteins in the pathophysiology of diabetic kidney disease (DKD). The JAK/STAT pathway is involved in the inflammatory response and endothelial cell dysfunction observed in DKD. The glucagon‐like peptide‐1 (GLP‐1) analog liraglutide is an effective treatment for type 2 diabetes because it improves the...
Paper Details
Title
Effect of liraglutide on the Janus kinase/signal transducer and transcription activator (JAK/STAT) pathway in diabetic kidney disease in db/db mice and in cultured endothelial cells
Published Date
Feb 28, 2019
Journal
Volume
11
Issue
8
Pages
656 - 664
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Notes
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