Mechanisms regulating zygotic genome activation
Abstract
Following fertilization, the two specified gametes must unite to create an entirely new organism. The genome is initially transcriptionally quiescent, allowing the zygote to be reprogrammed into a totipotent state. Gradually, the genome is activated through a process known as the maternal-to-zygotic transition, which enables zygotic gene products to replace the maternal supply that initiated development. This essential transition has been...
Paper Details
Title
Mechanisms regulating zygotic genome activation
Published Date
Dec 20, 2018
Journal
Volume
20
Issue
4
Pages
221 - 234
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History