NTRK1 is a positive regulator of YAP oncogenic function
Abstract
Multiple cancer signalling networks take part in regulatory crosstalks with the Hippo tumour suppressor pathway through the transcriptional cofactor Yes-associated protein (YAP). Nevertheless, how YAP is controlled by pathway crosstalks in tumourigenesis remains poorly understood. Here, we performed a targeted kinase inhibitor screen in human cancer cells to identify novel Hippo pathway regulators. Notably, we identified the nerve growth factor...
Paper Details
Title
NTRK1 is a positive regulator of YAP oncogenic function
Published Date
Dec 12, 2018
Journal
Volume
38
Issue
15
Pages
2778 - 2787
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