Regional Homogeneity and Multivariate Pattern Analysis of Cervical Spondylosis Neck Pain and the Modulation Effect of Treatment

Objects: We investigated brain functional alteration in patients with chronic neck pain (CSNP) compared to healthy controls (HCs), and the effect of intervention. Methods: 104 CSNP patients and 96 matched HCs were recruited. Patients received 4 weeks of treatment. Resting-state fMRI and Northwick Park Neck Pain Questionnaire (NPQ) were collected before and after treatment. Regional Homogeneity (rs-ReHo) and multivariate pattern analysis (MVPA)...