Coexpression network analysis linked H2AFJ to chemoradiation resistance in colorectal cancer

Neoadjuvant chemoradiotherapy (CRT) resistance is a complex phenomenon and it remains a major problem for patients with a priori resistant tumor. Therefore, there is a strong need to investigate molecular biomarkers which may guide for treatment decision‐making. In our study, weighted gene coexpression network analysis was applied to identify CRT‐resistance hub modules in 12 colorectal cancer (CRC) cell lines with different CRT sensitivities...