Characterization of single microvesicles in plasma from glioblastoma patients

Extracellular vesicles (EV) are shed by tumor cells but little is known about their individual molecular phenotypes and heterogeneity. While exosomes have received considerable attention, much less is known about larger microvesicles. Here we profile single microvesicles (MV) and exosomes from glioblastoma (GB) cells and MV from the plasma of patients. EV secreted from mouse glioma GL261 and human primary GBM8 cell lines as well as from the...