NF-κB Signaling Pathways in Carcinogenesis

Published: Dec 7, 2018
Abstract
Nuclear factor-kappaB (NF-κB) is a signal-activated transcription factor complex with two functional subunits and controls the expression of >600 genes in the human genome. This protein complex was initially identified and described as a nuclear protein complex uniquely present in cells that transcribe immunoglobulin light chain genes. Hence, its pro-oncogenic functions were studied only in the context of hematologic malignancies. However,...
Paper Details
Title
NF-κB Signaling Pathways in Carcinogenesis
Published Date
Dec 7, 2018
Journal
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