IL-12, IL-23 and IL-17 in IBD: immunobiology and therapeutic targeting.

Volume: 16, Issue: 3, Pages: 185 - 196
Published: Mar 1, 2019
Abstract
IL-12 and IL-23 are closely related cytokines with important roles in the regulation of tissue inflammation. Converging evidence from studies in mice, human observational studies and population genetics supports the importance of these cytokines in the regulation of mucosal inflammation in the gut in particular. Ustekinumab, a therapeutic antibody targeting both cytokines is now widely licensed for the treatment of Crohn's disease, including in...
Paper Details
Title
IL-12, IL-23 and IL-17 in IBD: immunobiology and therapeutic targeting.
Published Date
Mar 1, 2019
Volume
16
Issue
3
Pages
185 - 196
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.