Maintaining the proliferative cell niche in multicellular models of epithelia
Abstract
The maintenance of the proliferative cell niche is critical to epithelial tissue morphology and function. In this paper we investigate how current modelling methods can result in the erroneous loss of proliferative cells from the proliferative cell niche. Using an established model of the inter-follicular epidermis we find there is a limit to the proliferative cell densities that can be maintained in the basal layer (the niche) if we do not...
Paper Details
Title
Maintaining the proliferative cell niche in multicellular models of epithelia
Published Date
Oct 1, 2021
Volume
527
Pages
110807 - 110807
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